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Targeted Radionuclide Therapy (TRT) is an expanding field of cancer treatment in which radiopharmaceuticals—comprising a radionuclide linked to a tumour-targeting biological vector—are administered to deliver cytotoxic radiation doses selectively to malignant tissues. The growing development of theragnostic agents, enabling both imaging and therapy, has strengthened the rationale for a patient-specific treatment approach. In clinical trials, […] |
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This presentation provides an overview of fibroblast activation protein (FAP)–directed molecular imaging as a novel approach for tumour staging and theranostic decision-making across multiple malignancies. It introduces the biological role of cancer-associated fibroblasts and stromal remodeling in tumour progression and highlights the rationale for FAP-targeted PET imaging. Clinical evidence from prospective trials and comparative imaging […] |
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