Pretargeting Approach and Radiobiology

This course provides a comprehensive overview of pretargeting, a powerful strategy for targeted imaging and therapy in nuclear medicine.

The course duration is 3 hours.

• Nuclear Medicine physicians
• Radiologists
• Radiopharmacists and radiochemists
• Medical physicists
• Research scientists working in nuclear medicine and drug development
• Graduate students in related fields (e.g., biochemistry, radiochemistry)

• Explain the basic principles of pretargeting
• Describe the key components of the pretargeting approach, including targeting vectors, pretargeting molecules, and radioisotopes.
• Discuss the advantages and limitations of pretargeting compared to conventional radioimmunoconjugates.
• Analyze the specific steps involved in pretargeting with the Tz-TCO system.
• Evaluate the potential of other pretargeting systems beyond Tz-TCO.
• Explain the application of pretargeted PET/SPECT imaging in oncology and neuroscience.
• Discuss the therapeutic applications of pretargeting and its potential benefits.