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Treatment of Metastatic Bone Pain Using Bone-Seeking Agents
April 10, 2025 – 09:00 – April 11, 2025 – 16:00 CEST
Internal radiotherapy with bone-seeking agents is effective in delivering high doses of radiation to widespread metastatic bone lesions and may limit the radiation absorbed dose to healthy tissue. Beta emitter have long been preferred agents for bone pain palliation. The approval of 223Ra and data showing a prolonged survival with alpha emitter are favored in bone pain palliation. Unfortunately, we do not have good data on the survival after treatment with beta emitters. In the face-to-face course we will discuss the pathophysiology of bone pain to understand the principle of therapeutic effect of bone seeking agents. Dosimetry is essential to increase the dose to the tumor by limiting of severe side effects. All the focus is on the alpha emitters only, based on the poor data about survival data for the beta emitters. The future of therapy in Nuclear Medicine is the combination with other agents to improve the therapeutic effect, e.g. chemotherapy, immunotherapy or anti-androgen therapy.
Learning Objectives
- Pathophysiology and medical treatment of bone pain
- Pro/con alpha/beta emitters
- Performing of dosimetry
- Combination treatment to improve the therapeutic effect
Target Audience
- Nuclear medicine physician, junior or senior, with an interest in treatment
Faculty

Knut Liepe
SpeakerFrankfurt (Oder), Germany

Tatiana Louro
SpeakerLisbon, Portugal

Giulia Santo
SpeakerCatanzaro, Italy
Registration Details
Course Fee € 950.-
Registration Fee includes:
- Electronic Course Book, including all Slides
- Coffee & Lunch Breaks
Registration Fee does NOT include:
- Travel to the Venue
- Accommodation
Registration fees need to be paid 1 week prior to the event. In case the payment is not received by this deadline, the registration needs to be cancelled. Payment can be settled by Credit Card Cheques will not be accepted
Cancellations must be notified in writing to the EANM Office. Telephone cancellations cannot be accepted. Substitutions will be accepted if the name and e-mail address of the substitute are sent to the EANM Office 4 weeks prior to the event. In the case of cancellation 4 weeks before the course, we will refund you the fee less a € 100,- administration charge. After this date, we cannot grant any refund for cancellations. Any refund will take place after the respective course. EANM will not be held liable for cancellation fees of hotels, airlines or other means of transportation.